Publications

PEER-REVIEWED PUBLICATIONS

Original Studies:

Cobrin A, Blois S, Abrams-Ogg A, Kruth S, Dewey C, Holowaychuk M, Gauthier V. Neutrophil gelatinase-associated lipocalin in dogs with chronic kidney disease, carcinoma, lymphoma, and endotoxaemia. J Small Animal Pract 2016 Apr 26. doi: 10.1111/jsap.12481. [Epub ahead of print].

Jagodich TA and Holowaychuk MK. Transfusion practice in dogs and cats: an internet-based survey. J Vet Emerg Crit Care 26(3):360-72, 2016.

Guieu LV, Bersenas AM, Holowaychuk MK, Brisson BA, Weese JS. Serial evaluation of abdominal fluid and serum amino-terminal pro-C type natriuretic peptide in dogs with septic peritonitis. J Vet Intern Med 29(5):1300-6, 2015.

Holowaychuk MK and Musulin SE.  The effect of blood usage protocol on the age of packed red blood cell transfusions administered at 2 veterinary teaching hospitals. J Vet Emerg Crit Care 25(5):679-83, 2015.

Gauthier V, Holowaychuk MK, Kerr CL, Bersenas AME, Wood RD. Effect of synthetic colloid administration on coagulation in healthy dogs and dogs with systemic inflammation. J Vet Int Med 29(1):276-285, 2015.

Holowaychuk MK, Fujita H, Bersenas AME. Evaluation of a transcutaneous blood gas monitoring system in critically ill dogs. J Vet Emerg Crit Care 24(5):545-553, 2014.

Floras ANK, Holowaychuk MK, Bienzle D, Bersenas AME, Sharif S, Harvey T, Nordone SK, Wood G. N-terminal pro-C-natriuretic peptide and cytokine kinetics in dogs with endotoxemia. J Vet Intern Med 28(5):1147-1153, 2014.

Gauthier V, Holowaychuk MK, Kerr CL, Bersenas AME, Wood RD. Effect of synthetic colloid administration on hemodynamic and laboratory variables in healthy dogs and dogs with systemic inflammation. J Vet Emerg Crit Care 24(3):251-251, 2014.

Floras ANK, Holowaychuk MK, Hodgins DC, Marr HS, Birkenheuer A, Sharif S, Bersenas AME, Bienzle D. Investigation of a commercial ELISA for the detection of canine procalcitonin. J Vet Intern Med 28(2):599-602, 2014.

Holowaychuk MK, Hanel RM, Wood RD, Rogers L, O’Keefe K, Monteith G. Coagulation abnormalities in dogs following acute trauma: a prospective multicenter study. J Vet Emerg Crit Care 24(1):93-104, 2014.

Hall KE, Holowaychuk MK, Sharp CR, Reineke E. A multi-center eight-week prospective cohort study of 315 dogs sustaining trauma. J Am Vet Med Assoc 244(3):300-308, 2014.

Goldstein MR, Kruth SA, Bersenas AM, Holowaychuk MK, Weese JS. Detection and characterization of Clostridium perfringens in the feces of healthy and diarrheic dogs. Can J Vet Res 76(3):161-165, 2012.

Holowaychuk MK, Birkenheuer AJ, Li, J, Marr H, Boll A, Nordone SK. Alterations in calcium homeostasis in dogs with induced endotoxemia. J Vet Intern Med 26(2):244-251, 2012.

Boudreau AE, Bersenas AME, Kerr C, Holowaychuk MK, Johnson R. A comparison of three anesthetic protocols for 24 hours of mechanical ventilation in cats. J Vet Emerg Crit Care 22(2):239-252, 2012.

Holowaychuk MK, Hansen BD, DeFrancesco TC, Marks SL. Ionized hypocalcemia in critically ill dogs. J Vet Intern Med 23(3):509-513, 2009.

Retrospective Studies:

Sharma D and Holowaychuk MK. Retrospective evaluation of prognostic indicators in dogs with head trauma: 72 cases (January-March 2011). J Vet Emerg Crit Care 25(5):631-9, 2015.

Holowaychuk MK, Leader JL, Monteith G. Risk factors for post-transfusion complications and non-survival in dogs receiving packed red blood cell transfusions: 216 cases (2008-2011). J Am Vet Med Assoc 244(4):431-437, 2014.

Holowaychuk MK and Monteith G. Ionized hypocalcemia as a prognostic indicator in dogs following trauma. J Vet Emerg Crit Care 21(5):521-530, 2011.

Review Articles:

Holowaychuk MK. Top 5 ingestions that require induction of emesis. Clinician’s Brief October:18-22, 2015.

Holowaychuk MK. Top 5 ingestions that never require induction of emesis. Clinician’s Brief October:12-16, 2015.

Hanel RM, Chan DL, Conner B, Gauthier V, Holowaychuk M, Istvan S, Walker JM, Wood D, Goggs R, Wiinberg B. Systematic evaluation of evidence on veterinary viscoelastic testing. Part 4: Definitions and data reporting. J Vet Emerg Crit Care 24(1):47-56, 2014.

Holowaychuk MK. Hypocalcemia of critical illness. Vet Clin North Am Small Anim 43(6):1299-1317, 2013.

Holowaychuk MK and Martin LG. Review of hypocalcemia in septic patients. J Vet Emerg Crit Care 17(4):348-358, 2007.

Holowaychuk MK, Hansen BD, Marks SL, Hanel RM, Mariani CL. Head trauma. Standards of Care Emergency and Critical Care Medicine 9(6):1-8,16, 2007.

Holowaychuk MK, Marks SL, Hansen BD, DeFrancesco TC. Pulmonary contusions. Standards of Care Emergency and Critical Care Medicine 8(10):1-6, 2006.

Holowaychuk MK, Marks SL, Hansen BD, DeFrancesco TC. Peritoneal dialysis. Standards of Care Emergency and Critical Care Medicine 8(11):5-10, 2006.

Holowaychuk MK and Martin LG. Misconceptions about emergency and critical care: Cardiopulmonary cerebral resuscitation, fluid therapy, shock, and trauma. Compend Contin Educ Pract Vet 28(6):420-433, 2006.

Holowaychuk MK and Martin LG. Misconceptions about emergency and critical care: Metabolic disease and intensive care medicine. Compend Contin Educ Pract Vet 28(6):434-448, 2006.

Case Reports/Case Series:

Blois S, Holowaychuk M, Wood R. Evaluation of thromboelastography in two Factor XII deficient cats. J Fel Med Surg Open Reports January-June 1(1):2055116915585025, 2015.

Sabino CV, Holowaychuk M, Bateman S. Management of acute respiratory distress syndrome in a French bulldog using airway pressure release ventilation. J Vet Emerg Crit Care 23(4):447-454, 2013.

Di Mauro FM and Holowaychuk MK. Intravenous administration of desmopressin acetate to reverse acetylsalicylic acid-induced coagulopathy in three dogs. J Vet Emerg Crit Care 23(4):455-458, 2013.

Boyle TE, Holowaychuk MK, Adams AK, Marks SL. Successful treatment of congestive heart failure in three cats with hyperviscosity syndrome using plasmapheresis. J Am Anim Hosp Assoc 47(1):50-55, 2011.

Sikorski LE, Birkenheuer AJ, Holowaychuk MK, McCleary-Wheeler AL, Davis JM, Littman MP. Babesiosis caused by a large Babesia species in 7 immunocompromised dogs. J Vet Intern Med 24(1):127-131, 2010.

Shearer LR, Boudreau AE, Holowaychuk MK. Distal renal tubular acidosis and immune-mediated hemolytic anemia in 3 dogs. J Vet Intern Med 23(6):1284-1288, 2009.

Holowaychuk MK. Renal failure in a guinea pig (Cavia porcellus) following ingestion of oxalate containing plants. Can Vet J 47(8):787-9, 2006.

ABSTRACT PUBLICATIONS

Guieu LVS, Bersenas AME, Brisson B, Holowaychuk MK, Weese JS, Ammersbach M, Beaufrere H, Fujita H. Daily post-operative evaluation of peripheral blood and abdominal drain fluid from dogs with closed suction abdominal drains to identify septic peritonitis following gastrointestinal surgery. J Vet Emerg Crit Care 24(S1):S7, 2014.

Holowaychuk MK, Solomon SB, Hansen BD. Hypocalcemia is associated with more severe shock and decreased survival in a canine model of sepsis. J Vet Emerg Crit Care 23(S1):S7-S8, 2013.

Hall K, Sharp C, Holowaychuk M, Reineke E. A multi-center eight-week prospective cohort study of 30 dogs sustaining trauma. J Vet Emerg Crit Care 22(S2):S6, 2012.

Sharma D and Holowaychuk MK. Prognostic indicators in dogs with head trauma. J Vet Emerg Crit Care 22(S2):S9, 2012.

Gauthier VG, Holowaychuk MK, Kerr CL, Bersenas AM, Wood RD. Effect of synthetic colloid administration on coagulation parameters in healthy dogs and dogs with systemic inflammation. J Vet Emerg Crit Care 22(S2):S5, 2012.

Holowaychuk M, Hanel R, O’Keefe K, Rogers L, Monteith G, Wood D. Prognostic value of coagulation parameters in dogs following trauma. J Vet Emerg Crit Care 21(S1):S1, 2011.

Holowaychuk MK, Birkenheuer AJ, Li J, Marr H, Boll A, Nordone SK. Alterations in calcium homeostasis in dogs with induced endotoxemia. J Vet Emerg Crit Care 20(S1):A5, 2010.

Anastasio JD, Waddell LS, Holowaychuk MK, Cunz H, Craft EM, Powell LL, Smith KF, Julius T, Claire MC, Rudloff E, Sharp CR, Rozanski EA. Treatment approach and outcome in cats with pyothorax: 152 cases. J Vet Emerg Crit Care 20(S1):A1, 2010.

Boudreau AE, Bersenas A, Kerr C, Johnson R, Holowaychuk M. A comparison of three sedation protocols to facilitate mechanical ventilation in cats. J Vet Emerg Crit Care 20(S1):A1-A2, 2010.

Martin LG, Behrend EN, Holowaychuk MK, Grad NL, Lee HP. Comparison of low-dose and standard-dose ACTH stimulation tests in critically ill dogs by assessment of serum total and free cortisol concentrations. J Vet Intern Med, 24(3):685, 2010.

Holowaychuk MK, Hansen BD, DeFrancesco TC, Marks SL. Evaluation of ionized calcium in critically ill dogs. J Vet Emerg Crit Care 17(3)(S1):S5, 2007.

SCIENTIFIC POSTER PRESENTATIONS

Abrams-Ogg A, Ho K, Blois S, Mathews K, Holowaychuk M, Bersenas A, Wood D. Activated clotting time (ACT) in healthy sedated cats using the MAX-ACT® system. American College of Veterinary Internal Medicine Forum, Indianapolis, IN, June 2015.

Floras ANK, Holowaychuk MK, Harvey T, Bienzle D, Bersenas AME, Sharif S, Wood GA. N-terminal pro-C-natriuretic peptide and cytokine kinetics in dogs with systemic inflammation. International Veterinary Emergency and Critical Care Society Meeting, San Diego, CA, September 2013.

Gauthier VG, Holowaychuk MK, Kerr CL, Bersenas AM, Wood RD. Effect of synthetic colloid administration on clinical and laboratory parameters in healthy dogs and dogs with systemic inflammation. International Veterinary Emergency and Critical Care Society Meeting, San Antonio, TX, September 2012.

Jagodich TA and Holowaychuk MK. Transfusion practice in veterinary medicine: An internet-based survey. Merck-Merial Veterinary Scholars Program (MMVSP), Denver, CO, August 2012.

Leader J, Holowaychuk M, Monteith G. The effect of packed red blood cell age on mortality, transfusion reactions, and post-transfusion complications. Ontario Veterinary College Summer Leadership and Research Program Poster Presentations, Guelph, ON, August 2011.

O’Keefe K, Holowaychuk M, Hanel R, Rogers L, Monteith G, Wood D. Evaluation of coagulation in dogs following acute trauma. Merck-Merial Veterinary Scholars Program (MMVSP), Athens, GA, August 2010.

Rogers L, Holowaychuk M, Hayes G. Prognostic indicators in dogs following acute trauma. Merck-Merial Veterinary Scholars Program (MMVSP), Raleigh, NC, August 2009.

BOOK CHAPTERS

Holowaychuk MK. Colloid Fluid Therapy in The Textbook of Small Animal Emergency Medicine, Wiley-Blackwell (under review).

Holowaychuk MK and Yagi K. Evolution of Veterinary Transfusion Medicine and Blood Banking in Manual of Veterinary Transfusion Medicine and Blood Banking, Wiley-Blackwell (in press).

Holowaychuk MK and Day TK. Hemoglobin-based Oxygen Carrier (HBOC) Solutions in Manual of Veterinary Transfusion Medicine and Blood Banking, Wiley-Blackwell (in press).

Holowaychuk MK and Yagi K. Miscellaneous Blood Product Usage in Manual of Veterinary Transfusion Medicine and Blood Banking, Wiley-Blackwell (in press).

Holowaychuk MK. Limiting Allogenic Blood Transfusions in Manual of Veterinary Transfusion Medicine and Blood Banking, Wiley-Blackwell (in press).

Holowaychuk MK and Ostenkamp SM. Care of the Patient with Intracranial Disease in Advanced Monitoring and Procedures for Small Animal Emergency and Critical Care, Wiley-Blackwell, pp 789-798, 2012.

NON PEER-REVIEWED PUBLICATIONS

Holowaychuk MK. Clinical assessment and management of bleeding patients. Canadian Vet. Volume 11, No. 3, May/June, 2016.

Holowaychuk MK. Diagnosis and management of sepsis in small animals. Canadian Vet. Volume 10, No. 6, November/December, 2015.

Holowaychuk MK. Treating cats in shock: they’re not just small dogs. Canadian Vet Tech. Volume 6, No. 4, Fall 2014.

Holowaychuk MK. Breaking the silence: Medical errors and what we can learn. Canadian Vet Tech. Volume 6, No. 3, Summer 2014.

Holowaychuk MK. Triage and management of trauma cases: Acting quickly and effectively. Small Animal Veterinary Rounds. Volume 1, Issue 3, 2011.

Holowaychuk MK. New frontiers in critical care: Advances in medical knowledge help clinicians provide the best care for their critically ill patients. Magazine for the North Carolina State University College of Veterinary Medicine Summer, 2007.

SCIENTIFIC CONFERENCE PROCEEDINGS

Hydroxyethyl starches and acute kidney injury; Monitoring gastric residual volume; The role of vitamin D in infection and critical illness. International Veterinary Emergency and Critical Care Society Meeting, Indianapolis, IN, 2014.

Current transfusion practice: Results of an internet survey; Transcutaneous blood gas monitoring in the small animal ICU; Central venous pressure monitoring: underused or obsolete?; Breaking the silence: medical errors and what we can learn. International Veterinary Emergency and Critical Care Society Meeting, San Diego, CA, 2013.

Endotoxemia as a model for canine sepsis; Abnormalities in calcium homeostasis during canine sepsis. American College of Veterinary Internal Medicine Forum, New Orleans, LA, 2012.

Coagulopathy of trauma; Canine and feline sepsis: Year in review. International Veterinary Emergency and Critical Care Society Meeting, Nashville, TN, 2011.

Canine sepsis models: What have we learned? International Veterinary Emergency and Critical Care Society Meeting, San Antonio, TX, 2010.